PeptideSynthNJ said:Distribution matters less than total but it is not nothing.
DEXA scan update relevant to protein intake:
Scanned at months 0, 6, and 12. Here are the body comp numbers:
| Baseline | Month 6 | Month 12 | |
|---|---|---|---|
| Total mass | 251 lbs | 236 lbs | 208 lbs |
| Fat mass | 111 lbs | 71 lbs | 43 lbs |
| Lean mass | 149 lbs | 154 lbs | 155 lbs |
| Body fat % | 44% | 34% | 22% |
Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The protein intake discussion needs to include body comp data, not just scale weight.
Following on from PharmD_Rodriguez — and this may be the naive question:
How people are hitting a protein target on a genuinely suppressed appetite, because volume is the binding constraint rather than willingness?
lisa_labSD said:DEXA scan update relevant to protein intake: Scanned at months 0, 6, and 12.
Adding the part of the answer the thread has not reached. The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously. On the positive side: reduced anxiety around food, better self-image, more confidence. On the difficult side: grief for the years lost, identity disruption, relationships built around eating, and the loss of food as a coping mechanism with nothing put in its place. Rarer but real: anhedonia and emotional flatness. Regulators have started asking for validated patient-reported outcomes in this class; the existing data gap is not evidence of absence.
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Shop Reference StandardsOP back with an update, since a thread like this is useless without one.
Front-loading was the answer. Same total intake, same drug, but two thirds of the protein before midday and I am hitting the target most days now.
paige_pharma said:The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.
True, and anyone with reduced kidney function needs that target set by a clinician rather than a forum. High protein is safe in normal kidneys and is not automatically safe in impaired ones.
Correct me if the detail matters more than I have assumed.