LabKate said:Sharing my comprehensive lab data relevant to lean mass: Biomarker Baseline Month 3 Month 6 Month 9 Weight (lbs) 274 249 234 199 A1C (%) 7.4 6.4 5.5…
Physical therapist weighing in on lean mass. I work with bariatric and metabolic patients daily.
The resistance training evidence is critical here:
The Lundgren 2024 JAMA paper[1] showed that structured resistance training preserved 73% more lean mass in GLP-1 patients vs medication alone. When discussing lean mass, we MUST include the exercise component.
My minimum prescription: 3x/week compound movements (squat, deadlift, press, row), progressive overload, 7-10K steps/day, and 1.2-1.6g protein/kg/day.
[1] Lundgren JR, et al. JAMA. 2024;331(1):38-48.
LabKate said:Sharing my comprehensive lab data relevant to lean mass: Biomarker Baseline Month 3 Month 6 Month 9 Weight (lbs) 274 249 234 199 A1C (%) 7.4 6.4 5.5…
Thank you — that is the clearest version of this I have read, and I have read a lot of them.
Clinical perspective, offered as context rather than as advice.
DEXA scan update relevant to lean mass:
Scanned at months 0, 6, and 12. Here are the body comp numbers:
| Baseline | Month 6 | Month 12 | |
|---|---|---|---|
| Total mass | 255 lbs | 235 lbs | 202 lbs |
| Fat mass | 105 lbs | 75 lbs | 52 lbs |
| Lean mass | 158 lbs | 154 lbs | 149 lbs |
| Body fat % | 40% | 34% | 21% |
Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The lean mass discussion needs to include body comp data, not just scale weight.
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Browse GL BiochemDr.GutHealth said:DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.
This matches mine closely enough to be worth saying so out loud. Posting only so the count is not one.
Dr.GutHealth said:DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.
There is a second half to this that has not been said yet. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.