JakeSmashed95 said:

Update — tachyphylaxis to the gastric effect, persistence of the appetite effect.

Pushing back on JakeSmashed95 here. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

That is the short version; the long version is somebody else's post.

JakeSmashed95 said:

Update — tachyphylaxis to the gastric effect, persistence of the appetite effect.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.