Dr.Martinez said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
One thing that is still open after Dr.Martinez’s answer:
Whether an unchanged LDL-C alongside a large triglyceride fall is a good result or a bad one, because ApoB and LDL-C seem to be telling different stories?
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Shop Reference Standardslabquiet_amy said:If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.
I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.
labquiet_amy said:If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.
That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.