Triglycerides dropped by half, HDL barely moved, and my calculated LDL is almost exactly where it started, which is not the outcome I had been promised.
What I am trying to establish is whether an unchanged LDL-C alongside a large triglyceride fall is a good result or a bad one, because ApoB and LDL-C seem to be telling different stories.
Practical detail welcome, however dull — the duller the better.
CryptoCarl said:Triglycerides dropped by half, HDL barely moved, and my calculated LDL is almost exactly where it started, which is not the outcome I had been…
Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data:
| Category | Marker | Before | After 11mo | Change |
|---|---|---|---|---|
| Metabolic | A1C | 7.2% | 5.7% | ⬇️ 1.4% |
| Metabolic | Fasting Glucose | 116 | 88 | ⬇️ 36 |
| Lipids | LDL | 159 | 103 | ⬇️ 51 |
| Lipids | Triglycerides | 231 | 106 | ⬇️ 101 |
| Inflammation | hsCRP | 8.5 | 0.9 | ⬇️ 6.0 |
Every single metabolic marker improved. This is why I'm a believer in this therapy.
Dr.RenalNash said:Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data: Category Marker Before After…
Tracking labs for the lipid panel — here's the panel I get every 3 months and why:
- CMP: glucose, electrolytes, kidney function, liver enzymes
- Lipid panel: total cholesterol, LDL, HDL, triglycerides
- A1C: 3-month glucose average
- hsCRP: inflammatory marker
- CBC: blood counts, anemia screening
- B12, folate, iron: nutritional deficiency screening
- TSH, free T4: thyroid monitoring
- Lipase: pancreatic safety check
Total cost with insurance: about $38 copay. Without insurance, request cash-pay pricing from Quest/Labcorp — usually $173.
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Browse GL BiochemCryptoCarl said:Triglycerides dropped by half, HDL barely moved, and my calculated LDL is almost exactly where it started, which is not the outcome I had been…
Can confirm. Same sequence, different timescale. Posting only so the count is not one.
Adding the clinical framing, because it changes how the question reads.
Omega-3 index improvement on the lipid panel: often overlooked but my omega-3 index went from 4.2% to 8.7% over 11 months. I supplemented with 2g EPA+DHA daily.
This matters because omega-3s are anti-inflammatory and cardioprotective, complementing the GLP-1 benefits. Target omega-3 index is >8%. Combined with the triglyceride reduction from the medication, my lipid profile is the best it's been in decades.