Dr.SportsMedIN said:The distinction that resolves most of these threads is between what is true on average and what is true for one person.
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
Correct me if the detail matters more than I have assumed.
HPLC_Greg said:Agreed, and the adaptation point cuts both ways: tachyphylaxis to gastric emptying is why tolerability improves, and it is also why people who were…
Saving this. It is the first explanation that did not require me to already understand it.
Dr.SportsMedIN said:The distinction that resolves most of these threads is between what is true on average and what is true for one person.
This is where I part company with the consensus forming above. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.
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View ResultsOne concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.