Dr.PulmRoch said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.
JessicaH_TX said:The pharmacokinetics explain nearly every practical question asked here.
Thank you — that is the clearest version of this I have read, and I have read a lot of them. Printing the relevant bit and taking it with me.
Dr.PulmRoch said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
This is where I part company with the consensus forming above. The objection nobody has made: this only works if the measurement is doing what we assume it is doing, and that assumption has not been tested here.
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Browse GL BiochemOne concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.