newstart_MO said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Can confirm. Same sequence, different timescale. I had assumed I was the exception until I read this.
Clinical perspective, offered as context rather than as advice. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
TrialNerd_Beth said:If two explanations both fit, the useful question is which one predicts something the other does not.
Adding a me-too, because a thread of one person's experience is not much use. The detail I would add is minor and it is already implied above.
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Shop Reference StandardsTrialNerd_Beth said:If two explanations both fit, the useful question is which one predicts something the other does not.
There is a second half to this that has not been said yet. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.